Batuhan Ayci

I am a postdoctoral fellow in the Department of Neurology at the Icahn School of Medicine at Mount Sinai, where I work in Beck's Lab with Erin Beck, MD, PhD. My research focuses on multiple sclerosis, neuroimmunology, and advanced MRI markers of inflammatory demyelinating disease.

My current work uses 3T and 7T MRI to study cortical lesions, paramagnetic rim lesions, volumetrics, quantitative MRI metrics, and the natural history of radiologically isolated syndrome. I also collaborate on deep learning approaches for MS lesion segmentation and cortical lesion detection.

I received my MD with high honor from Istanbul University-Cerrahpasa in 2024. Before joining Mount Sinai, I worked across neurology, neuroimmunology, and biomedical engineering settings in Turkey, Switzerland, and the United States.

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Photo of Batuhan Ayci

Icahn School of Medicine at Mount Sinai
Department of Neurology
Beck's Lab, New York, NY

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Clinical Experience

Research Experience

Education

Research Interests

My research interests are centered on clinical neuroimmunology and imaging biomarkers in multiple sclerosis. Specific areas include cortical demyelination, paramagnetic rim lesions, radiologically isolated syndrome, quantitative MRI, high-field MRI, automated lesion segmentation, and clinically meaningful computational imaging.

Selected Publications

Cortical Lesions Cortical Lesions Form Predominantly in Early Multiple Sclerosis
Ayci B, Dereskewicz E, dos Santos Silva J, Galasso J, Rust P, La Rosa F, Liu J, Reich DS, Sumowski JF, Beck ES
medRxiv, 2026
First-author preprint on when cortical lesions form over the course of multiple sclerosis.
Brain Aging Dose-Response New Lesion Formation Is Associated With Accelerated Brain Aging in Multiple Sclerosis
La Rosa F, Dos Santos Silva J, Dereskewicz E, Onyemeh K, Ayci B, Sizer E, Shashkova E, Garcia N, Graney R, Levy S, Katz Sand I, Sumowski JF, Beck ES
medRxiv, 2026
Co-authored preprint showing new MS lesion formation accelerates brain aging, with normalization once lesions stop forming.
CNN Segmentation A Novel Convolutional Neural Network for Automated Multiple Sclerosis Brain Lesion Segmentation
Dereskewicz E, La Rosa F, Dos Santos Silva J, Sizer E, Kohli A, Wynen M, Mullins WA, Maggi P, Levy S, Onyemeh K, Ayci B, Solomon AJ, Assländer J, Al-Louzi O, Reich DS, Sumowski J, Beck ES.
Journal of Neuroimaging, 2025. DOI: 10.1111/jon.70085
Co-authored convolutional neural network for automated MS brain-lesion segmentation.
Biomarkers Assessing the Relative Importance of Imaging and Serum Biomarkers in Capturing Disability, Cognitive Impairment, and Clinical Progression in Multiple Sclerosis
Cagol A, Benkert P, Schaedelin S, Ocampo-Pineda M, Montobbio N, Lu PJ, Ayci B, Wenger A, Shukur AA, Kaim K, Melie-Garcia L, Weigel M, Signori A, Calabrese P, Kappos L, Sormani MP, Kuhle J, Granziera C.
Advanced Science, 2026. DOI: 10.1002/advs.202512946
Co-authored comparison of imaging versus serum biomarkers for MS disability, cognition, and progression.
Neurobehcet Neurobehcet Syndrome
Ayci B, Gulec B, Uygunoglu U, Siva A.
In: Neuroimmunology. Turkish Neurological Society Publications, 2023
First-author Turkish-language book chapter on Neuro-Behçet syndrome.

Selected Presentations

Service & Recognition

  • Summit Best Poster Award, ACTRIMS Forum, 2026.
  • European Academy of Neurology Student Teaser Fellowship, 2023.

Source code adapted from Jon Barron's public academic website source code.